The potential use of coenzyme Q10 supplements alone or in combination with other drug therapies and nutritional supplements may help prevent or treat some of the following conditions: cardiovascular diseases, high blood pressure, cancer, periodontal diseases, mitochondrial disorders, radiation injury, obesity, diabetes, Parkinson's disease, acquired immune deficiency syndrome AIDS , gastric ulcers, allergy, migraine headaches, kidney failure, muscular dystrophy, and aging.
CoQ10 plays a significant role in boosting the immune system and physical performance, as tissues and cells involved with immune function are highly energy-dependent and therefore require an adequate supply of CoQ10 for optimal function. Primary dietary sources of CoQ10 include oily fish such as salmon and tuna , organ meats such as liver , and whole grains.
Most individuals obtain sufficient amounts of CoQ10 through a balanced diet, but supplementation may be useful for individuals with particular health conditions. CoQ10 is available as a supplement in several forms, including soft gel capsules, oral spray, hard shell capsules, and tablets.
A typical CoQ10 dosage is 30 to 90 mg per day, taken in divided doses, but the recommended amount can be as high as mg per day. CoQ10 is fat-soluble, so it is better absorbed when taken with a meal that contains oil or fat.
The clinical effect is not immediate and may take up to eight weeks. Side effects of CoQ10 may include diarrhea and rash; safety of Co q10 in pregnant or nursing women, or children has not been established.
It is an effective antioxidant both on its own and in fusion with vitamin E and is fundamental in powering the body's energy production ATP cycle. CoQ10 is found throughout the body in cell membranes, especially in the mitochondrial membranes, and is chiefly abundant in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. This publication is not copyrighted and is in the public domain.
Duplication is encouraged. NCCIH has provided this material for your information. It is not intended to substitute for the medical expertise and advice of your health care provider s. We encourage you to discuss any decisions about treatment or care with your health care provider. Found in almost every cell of the body, CoQ10 is a fat-soluble, vitamin-like substance that helps convert food into energy. A powerful antioxidant that protects against damage from toxic free radicals, CoQ10 is produced by the body and is also found in many foods , with higher levels in organ meats, such as liver or kidneys; as well as sardines, mackerel, chicken, cauliflower, broccoli and asparagus.
There are two forms of CoQ ubiquinone and ubiquinol. Ubiquinol, the active antioxidant form of CoQ10, is made in the body from ubiquinone. As we age, the levels of both forms drop. As early as age 20, the amount of ubiquinone our bodies produce begins to drop. Compounding the problem, the body also loses its ability to make ubiquinol from ubiquinone.
Most dietary supplements contain ubiquinone and are relatively cost effective, while ubiquinol supplements, which may be of most benefit as we age, can be harder to find and more expensive. Levels of CoQ10 in your body decrease as you age. CoQ10 levels have also been found to be lower in people with certain conditions, such as heart disease, and in those who take cholesterol-lowering drugs called statins. CoQ10 is found in meat, fish and nuts. The amount of CoQ10 found in these dietary sources, however, isn't enough to significantly increase CoQ10 levels in your body.
CoQ10 dietary supplements are available as capsules, chewable tablets, liquid syrups, wafers and by IV. CoQ10 might help prevent or treat certain heart conditions, as well as migraine headaches. Research on CoQ10 use for specific conditions and activities shows:. CoQ10 supplements might be beneficial for treating conditions such as congestive heart failure and preventing migraines. CoQ10 is considered safe, with few side effects. However, be sure to take this supplement under your doctor's supervision.
CoQ10 supplements appear to be safe and to produce few side effects when taken as directed. The safety of use of CoQ10 during pregnancy and breast-feeding hasn't been established.
Don't use CoQ10 if you're pregnant or breast-feeding without your doctor's approval. There is a problem with information submitted for this request.
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